ASTM E2525-2008 评定纳米粒子材料费对老鼠粒细胞巨噬细胞集落形成影响的标准试验方法
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【英文标准名称】:StandardTestMethodforEvaluationoftheEffectofNanoparticulateMaterialsontheFormationofMouseGranulocyte-MacrophageColonies
【原文标准名称】:评定纳米粒子材料费对老鼠粒细胞巨噬细胞集落形成影响的标准试验方法
【标准号】:ASTME2525-2008
【标准状态】:现行
【国别】:美国
【发布日期】:2008
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:E56.02
【标准类型】:(TestMethod)
【标准水平】:()
【中文主题词】:
【英文主题词】:bonemarrow;CFU-GM;clonogenicassay;granulocyte;macrophage;myelosuppression;nanoparticles;preclinicaldevelopment;stemcells
【摘要】:Stemcellsofhematopoieticoriginarepluripotentialandmaybeparticularlysensitivetotheeffectsofstimulationbynanoparticulatematerials.TheeffectofparticlesonmacrophageresponseshasanextensivehistoryandcanbeassessedbyPracticeF1903.Thetestmethoddescribedherewillassesstheeffectonstemcellswhichcanbeprogenitorcellstothemacrophageline.1.1Thistestmethodprovidesaprotocolforquantitativeanalysisoftheeffectofnanoparticulatematerialsinphysiologicsolutionongranulocyte-macrophagecolony-formingunits.1.2Thistestmethodemploysmurinebonemarrowhematopoieticstemcellswhichproliferateanddifferentiatetoformdiscretecellclustersorcolonieswhicharecounted.1.3Thistestmethodispartoftheinvitropreclinicalcharacterizationcascadefornanoparticulatematerialsforsystemicadministrationinmedicalapplications.1.4Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappropriatesafetyandhealthpracticesanddeterminetheapplicabilityofregulatorylimitationspriortouse.
【中国标准分类号】:C04
【国际标准分类号】:07_100_10
【页数】:5P.;A4
【正文语种】:英语
【原文标准名称】:评定纳米粒子材料费对老鼠粒细胞巨噬细胞集落形成影响的标准试验方法
【标准号】:ASTME2525-2008
【标准状态】:现行
【国别】:美国
【发布日期】:2008
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:E56.02
【标准类型】:(TestMethod)
【标准水平】:()
【中文主题词】:
【英文主题词】:bonemarrow;CFU-GM;clonogenicassay;granulocyte;macrophage;myelosuppression;nanoparticles;preclinicaldevelopment;stemcells
【摘要】:Stemcellsofhematopoieticoriginarepluripotentialandmaybeparticularlysensitivetotheeffectsofstimulationbynanoparticulatematerials.TheeffectofparticlesonmacrophageresponseshasanextensivehistoryandcanbeassessedbyPracticeF1903.Thetestmethoddescribedherewillassesstheeffectonstemcellswhichcanbeprogenitorcellstothemacrophageline.1.1Thistestmethodprovidesaprotocolforquantitativeanalysisoftheeffectofnanoparticulatematerialsinphysiologicsolutionongranulocyte-macrophagecolony-formingunits.1.2Thistestmethodemploysmurinebonemarrowhematopoieticstemcellswhichproliferateanddifferentiatetoformdiscretecellclustersorcolonieswhicharecounted.1.3Thistestmethodispartoftheinvitropreclinicalcharacterizationcascadefornanoparticulatematerialsforsystemicadministrationinmedicalapplications.1.4Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappropriatesafetyandhealthpracticesanddeterminetheapplicabilityofregulatorylimitationspriortouse.
【中国标准分类号】:C04
【国际标准分类号】:07_100_10
【页数】:5P.;A4
【正文语种】:英语
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